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General Information

Some urological conditions have serious or life-threatening consequences and require immediate medical attention. These medical emergencies include

• acute urinary retention,
• Fournier's gangrene,
• paraphimosis,
• priapism, and
• testicular torsion.

While these conditions are unrelated and have different symptoms, they all require urgent care. Delaying treatment in some cases can result in surgical removal of testicles (orchiectomy), permanent inability to achieve an erection (impotence), or death.

Acute Urinary Retention

Acute urinary retention is the sudden inability to urinate and is usually symptomatic of another condition that needs treatment.

Incidence and Prevalence
Anyone can experience acute urinary retention. The causes and rate of occurrence varies greatly between genders until about age 60, when men are more often affected as a result of benign prostatic hyperplasia (BPH).

Risk Factors

Prostate cancer, prostatitis, and BPH are risk factors in men. Pregnant women, diabetics, and those who have had recent gynecological surgery are at higher risk.

Causes

Acute urinary retention is caused by obstruction in the bladder or the tube that carries urine from the bladder outside the body (urethra), a disruption of sensory information in the nervous system (e.g., spinal cord or nerve damage), or a situation or event that causes the bladder to become distended.

Factors associated with acute urinary retention include the following:

• Alcohol consumption
• Allergy or cold medications containing decongestants or antihistamines
• Certain prescription drugs (e.g., ipratropium bromide, albuterol, epinephrine) that cause the urethra to become narrow
• Delaying urination for a long time
• Long period of inactivity or bed rest
• Prolonged exposure to cold temperatures
• Spinal cord injury/nerve damage
• Surgery (e.g., complication of anesthesia)
• Urinary system obstruction (e.g., benign prostatic hyperplasia (BPH), bladder stones)
• urinary tract infection

Signs and Symptoms

Acute urinary retention produces severe lower abdominal pain, a distended abdomen, and/or the sudden inability to pass urine.

Complications that may develop with untreated urinary retention include bladder damage and chronic kidney failure.

Diagnosis

Diagnosis is based on a sudden lack of urinary output and bladder swelling (distention) observed during a physical examination.

Treatment

Treatment should be obtained within 5 hours of the onset of symptoms to avoid the development of complications. The underlying cause of urinary retention must be diagnosed and treated as well.

A small tube (catheter) is inserted into the bladder through the urethra to drain the urine. Catheterization relieves pain and distention.

Prognosis

Depending on the underlying cause, the recurrence rate can be up to 70% within a week after initial treatment. BPH is responsible for most recurrences.

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Paraphimosis Paraphimosis

Paraphimosis occurs when the fold of skin that covers the head (glans) of an uncircumcised penis (i.e., the foreskin) has been retracted and narrows below the glans, constricting the lymphatic drainage and causing the glans to swell. If not corrected, blood flow in the penis becomes impeded by the increasingly constricting band of foreskin, which causes further swelling of the glans. Because lack of oxygen from the reduced blood flow can cause tissue death (necrosis), paraphimosis is considered a medical emergency and requires immediate treatment.

Incidence and Prevalence
In the United States, paraphimosis occurs in about 1% of males over age 16. It can occur at any age but is most common during adolescence. Paraphimosis occurs in the elderly who need frequent catheterizations and those who have a history of poor hygiene or bacterial infections.

Risk Factors

Uncircumcised males are at risk. Piercing the penis increases the risk if the penile ring interferes with foreskin retraction or replacement over the glans, and if infection results from the piercing.

Causes

Causes include the following:

• Bacterial infection (e.g., balanoposthitis)
• Catheterization (i.e., if the foreskin is not returned to its original position after a urethral catheter is inserted, the glans may become swollen, which can initiate paraphimosis)
• Poor hygiene
• Swelling-producing injury
• Vigorous sexual intercourse

Symptoms include the following:

• Band of retracted foreskin tissue beneath the glans
• Black tissue on the glans (indicates necrosis)
• Inability to urinate (urinary retention)
• Penile pain
• Redness (erythema)
• Swollen glans (the shaft of the penis is not swollen)
• Tenderness

Complications

Tissue death caused by loss of blood supply (gangrene) and spontaneous detachment of diseased tissue (autoamputation) of the glans are possible complications of paraphimosis.

Diagnosis

Paraphimosis is diagnosed during a physical examination.

Treatment

Because paraphimosis can be severely painful, a pain reliever is administered before treatment. The first method of treatment after diagnosis involves manual manipulation of the penis to reduce swelling and to replace the foreskin over the glans. An ice pack may be applied to the penis (after the penis has been wrapped in plastic) to help reduce swelling.

Another option is to make a small incision in the foreskin to alleviate constriction and allow the swelling to subside. With this procedure, local anesthesia is administered to minimize discomfort.

After reduction of swelling is achieved, antibiotics are prescribed for any underlying infection.

Prognosis
Full recovery from paraphimosis is expected with prompt treatment.

Prevention

Circumcision is recommended after treatment to prevent a recurring episode.

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Priapism Priapism

Priapism is a prolonged, painful penile erection that occurs when blood in the penis is "trapped," or unable to drain. The stagnant blood causes an erection that can last from hours to days. A painful erection lasting for more than 4 hours indicates priapism. If not treated promptly, scarring and permanent inability to achieve an erection (impotence) can result.

Types

Veno-occlusive (low flow)
Veno-occlusive (blocked vein) priapism develops when circulation in the penis becomes sluggish due to obstructed veins. This type can occur without a known cause in men who are otherwise healthy. Most veno-occlusive priapism in men with sickle cell disease occurs between ages 19-21. The rate of veno-occlusive priapism is higher in men who have malaria, leukemia, and Fabry disease.

Arterial (high flow)
This rare, less painful type of priapism results from an injury to the penis or area between scrotum and anus (perineum) that prevents blood in the penis from circulating normally. It indicates a ruptured artery in the penis. There may be a lapse between the time of injury and onset of priapism. Incidence and Prevalence
Priapism can affect men of any age.

Risk Factors

Diseases that affect blood circulation may predispose men to developing the condition. Forty-two percent of men with sickle cell disease develop veno-occlusive priapism at least once.

Recreational or "party" drug use (e.g., cocaine, ecstasy, marijuana) is a risk factor. An overdose of injectable medication such as papaverine and phentolamine (Regitine®) for erectile dysfunction is also a risk factor. Men with sickle cell disease, leukemia, malaria, and Fabry disease are predisposed to priapism.

Alcohol consumption, androgenic steroids (used to increase muscle size), anticoagulants (Coumadin®, Warfilone®), and antihypertensives (Prazosin®) increase risk. Prolonged sexual activity is also a risk factor.

Causes

Priapism may develop as a result of prolonged sexual activity. Other causes include the following:

• Black widow spider bites
• Carbon monoxide poisoning
• Erectile dysfunction injection therapy (if amount of medication injected exceeds prescribed dose)
• Penile or perineal injury (e.g., perineal trauma against the top tube of a bicycle)
• Prescription antidepressive drugs trazodone (Desyrel®) and chlorpromazine (Compazine® , Serentil®)
• Spinal cord trauma
• Tumor

Signs and Symptoms

A painful penile erection that lasts 4 hours or more, and a soft head (glans) with a hard shaft are signs of priapism.

Diagnosis

Diagnosis includes a patient history and a physical examination to detect an injury or underlying problem.

Doppler sonogram (i.e., digital images of ultrasound echoes that detect poor blood flow) or penzel blood gas may be used to diagnose high- or low-flow priapism.

Treatment

There are several forms of treatment. Ice packs are applied to the penis and perineum to reduce swelling. Walking up a flight of stairs is sometimes effective, because mild exercise may divert blood flow to other areas of the body. The underlying injury (i.e., ruptured artery) causing arterial priapism is treated by tying off the artery (surgical ligation) to restore normal blood flow.

Intracavernous injection
Low-flow priapism is treated with vasoactive medications injected into the chambers in the penis that fill with blood to create an erection (corpora cavernosa). Alpha agonists terbutaline (Adrenalin®, Alupent®) and phenylephrine (Neo-Synephrine®) are commonly used.

Puncture
After numbing the area, a needle is used to drain the blood from the corpora cavernosa to allow the swelling to subside.

Surgical shunt
For veno-occlusive priapism, a passageway (shunt) may be surgically inserted to divert blood flow and reestablish circulation.

The underlying cause is treated when disease is present (e.g., leukemia, sickle cell disease).

Prognosis
The prognosis is good for both types of priapism when the condition is resolved quickly. When treatment is delayed, penile scarring and permanent impotence can result.

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Testicular Torsion Testicular Torsion

Testicular torsion is a disorder in which the testicles rotate (twist) and strangle the spermatic cord, which consists of blood vessels, lymphatic vessels, nerves, and the duct that carries sperm from the body (vas deferens), cutting off the blood supply to the testicles. Torsion can cause shrinkage (atrophy) and tissue death (necrosis), and may require surgical removal of the testicles (orchiectomy) if not treated promptly. Torsion often occurs during sleep.

Incidence and Prevalence
Testicular torsion primarily affects infants in the first year of life and adolescent boys age 12-18, although it can occur at any age.

Risk Factors

A variation of normal anatomy that causes the testicle to rotate on a horizontal axis is a risk factor.

Causes

Injury to the scrotum can initiate a muscle spasm that cause the testicles to twist. Some cases result from inadequate connective tissue that "anchors" the testicle within the scrotum. Many cases are idiopathic (i.e., have no known cause).

Signs and Symptoms

Symptoms include the following:

• Blood in semen
• Lower abdominal pain
• Lump in testicle
• Nausea and vomiting
• Sudden, severe testicular pain, followed by diminishing pain after several hours (after necrosis begins to set in)
• Redness of scrotum
• Swelling of one testicle

A patient history and physical examination is usually sufficient to diagnose testicular torsion. Testicular torsion may cause symptoms (e.g., testicular pain and swelling) similar to epididymitis (i.e., inflammation of the tubule where sperm is stored) and diagnostic tests may be necessary.

Color Doppler sonography (color printout of an ultrasound echo test) is used to identify the absence of blood flow typically found in a twisted testicle, which distinguishes the condition from epididymitis.

Urinalysis (analyzing chemical composition of urine) can be used to rule out bacterial infections.

Surgical exploration may be necessary if diagnosis cannot be made using other methods.

Treatment

Treatment involves untwisting (detorsion), manually if possible and surgically if necessary. Surgical detorsion requires anesthesia followed by an incision in the scrotum. The testicles are untwisted and evaluated for necrosis. Dead tissue is removed; removal of the affected testicle may be necessary. If necrosis has not occurred, the healthy testicle(s) are then sutured (stitched) to the scrotal wall to avoid recurrence.

Prognosis
If torsion is diagnosed and treated within 5-6 hours, the prognosis is good. The more time that elapses before resolution worsens the prognosis. After 18-24 hours, necrosis usually develops and indicates removal of the affected testicle (orchiectomy).

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