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Department of
Urology Intranet

Arie Belldegrun, MD

a Curriculum Vitae

Arie Belldegrun, MD
Professor of Urology
Chief, Division of Urologic Oncology
Roy and Carol Doumani Chair in Urologic Oncology


Phone: 310-206-1434
Educational Background
Medical School: 1967 - 1974 The Hebrew University Hadassah Medical School, Jerusalem, Israel
Residency: 1984 - 1985 Chief Resident, Harvard Program in Urology: Brigham and Women's Hospital, Boston, Massachusetts; West Roxbury Veterans Administration Medical Center; The Children's Hospital Medical Center, Boston, MA
1983 - 1984 Senior Resident, Harvard Program in Urology
1982 - 1983 Junior Resident, Harvard Program in Urology, Boston, Massachusetts
1980 - 1982 Resident in General Surgery, Beilinson Medical Center, Tel Aviv University, Sackler School of Medicine
1979 - 1980 Resident, Department of Urology and Renal Transplantation Unit, Beilinson Medical Center, Tel Aviv University, Sackler School of Medicine
1976 - 1979 Research Fellow and Visiting Scientist Weizmann Institute of Science, Rehovot, Israel
Board
Certifications
& Fellowships:
1985 - 1988 Fellow, Surgical Oncology, Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland

Professional Memberships
American Association for Cancer Research
American Association for Genitourinary Surgeons
The American Association of Immunologists
Fellow, American College of Surgeons
American Israeli Mecical Society
American Medical Association
American Society of Clinical Oncologists
American Urological Association, Inc.
The Clinical Immunology Society
European Society for Urological Oncology and Endocrinology
The International Transplantation Society
The Los Angeles Urologic Society
Society of Basic Urologic Research
Society for Biological Therapy
Society of University Surgeons
Society of Urologic Cryosurgeons
The Society of Urologic Oncology
Western Section, American Urological Association

Academic & Medical Staff Appointments
2000 - Roy and Carol Doumani Chair in Urologic Oncology, UCLA
1996 - Chief, Division of Urologic Oncology, Department of Urology, UCLA School of Medicine, Los Angeles, CA
1996 - Director of Urologic Research, Department of Urology, UCLA School of Medicine, Los Angeles, CA
1995 - Head, Genitourinary Oncology Program, Jonsson Comprehensive Cancer Center, Los Angeles, CA
1994 - Professor of Surgery/Urology, Head, Cancer Immunotherapy Program, Division of Urology, UCLA School of Medicine
1993 - Clinical Director, UCLA Prostate Disease Research Program
1993 - Surgical Director, UCLA Kidney Cancer Program
1990 - Associate Professor of Surgery/Urology, Head, Cancer Immunotherapy Program, Division of Urology, UCLA School of Medicine
1988 - Chief, Division of Urology, Olive-View Medical Center, Los Angeles, CA
1988 - Clinical Director, Adoptive Immunotherapy Core Laboratory, Jonsson Comprehensive Cancer Center, UCLA Center for the Health Sciences
1988-1994 - Associate Director, Genitourinary Oncology Program Area, Jonsson Comprehensive Cancer Center, UCLA Center for the Health Sciences
1988 - 1990 Assistant Professor of Surgery/Urology, Division of Urology, UCLA School of Medicine



Research & Clinical Interests
Cancer Vaccine, gene therapy, immunotherapy, Cytokine research, adoptive immunotherapy, tumor vaccines, molecular engineering of tumor cells and tumor infiltrating lymphocytes

Urologic oncology, clinical trials of biological therapy for advanced cancer, gene therapy

Awards & Honors
Surgical Forum Award, Boston Surgical Society, 1984
The Chaim/Weizmann Postdoctoral Fellowship Award, American Committee for the Weizmann Institute of Science, New York, NY, 1981/82
The Maimonides Award, The State of Israel Bonds, Los Angeles, CA, 1992
CaP Cure Award, Association for the Cure of Cancer of the Prostate, Washington, D.C., 1993
Trustee, The Prostate Cancer Charitable Trust, Imperial Cancer Research Fund, London, England, 1995
Who's Who in America, 1995
Strathmore's Who's Who, 1997-98
Elected Member, American Association of Genitourinary Surgeons


  Additional Information


Books:

 

Oliver RTD, Belldegrun A, Wrigley PFM Cancer Surveys. Cold Spring Harbour Laboratory Press, Plainview, New York, 1995.

Belldegrun A, Kirby RS, Newling DWW (ed.) New Perspectives in Prostate Cancer: Second Edition.  Isis Medical Media Ltd., Oxford, UK, 2000.

Belldegrun A, Ritchie A, Figlin R, Oliver R, Vaughan E (Ed): Renal and Adrenal Tumors. Biology and Management. Oxford University Press. UK, 2003.

 

 Patents/Biotechnology Affiliations

 

“Aggressive Prostate Cancer Clones Selected by Androgen Deprivation (LNCAP-A1 and LNCAP-A1/AD) and Uses Thereof”

M&A Ref. No:           30435.67USP1

Inventors:                   Cho-Lea Tso

                                     Arie Belldegrun, MD

 

“Novel Technique for Generating Dendritic Cells from DC14+ Precursors”

UCLA Preliminary Case No: LA98-097-01

Inventors:                   Andreas Hinkel, MD, PhD

                                     Arie Belldegrun, MD

 

“New Method of Gene Transfer into Dendritic Cells”

UCLA Preliminary Case No:

Inventors:                   Peter Mulders, MD, PhD

                                     Arie Belldegrun, MD

 

“PSA Positive Regulating (PSAR) Sequences and Uses Thereof”

U.S. Patent No. 6,110,702

U.S. Serial Number:  08/828,972    Filed March 27, 1997. Issued August 29, 2000.

UC Ref. No. 95-545-03

M&A Ref. No. 30435.35USU1

Inventors:                   Shen Pang, Ph.D.

                                     Arie Belldegrun, M.D.

 

“Novel Nucleic Acid Molecules Comprising the Prostate Specific Antigen (PSA) Promoter and Uses Thereof”

Initially Filed November 9, 1994

Improvements filed September 1, 1995 (Based on U.S. CIP Application S/N 08/522,841)

Assigned International Publication Number WO 96/14875, May 23, 1996

Inventors:                   Shen Pang, Ph.D, UCLA School of Medicine

                                     Arie Belldegrun, M.D., UCLA School of Medicine

 

“Aggressive Prostate Cancer Sublines Selected by Androgen Deprivation”

Initially Filed January 28, 1999

U.S. Serial No:  60/117,562

UC Ref. No: LA99-158-02

M&A Ref. No: 30435.67USU1

Inventors:                   Cho-Lea Tso, UCLA School of Medicine

                                     Arie Belldegrun, MD, UCLA School of Medicine

 

“Chimeric Transcriptional Regulatory Element Compositions and Methods for Increasing Prostate-Targeted Gene Expression”

International Patent No:  PCT/US00/28444

Recorded:  8/6/2002

Filing date: 4/15/2002

Serial Number: 10110681

UCLA Ref. No: 2000-124-3

Inventors:                   Lily Wu, MD, PhD, UCLA School of Medicine

                                     Michael Carey, PhD, UCLA School of Medicine

                                     Arie Belldegrun, MD, UCLA School of Medicine

          

“Human Monoclonal Antibodies to Epidermal Growth Factor Receptor and Therapies”

Initially Filed December 1, 2000

Serial No. 09/728,429

Ref No:  ABX-EGF-Dose

Inventors:                   Gisela Schwab, MD, Abgenix, Inc.

                                     Michelle Lohner, Abgenix, Inc.

                                     Lorin Roskos, Abgenix, Inc.

                                     Michael Gallo, Abgenix, Inc.

                                     Robert A. Figlin, MD, UCLA School of Medicine

                                     Arie Belldegrun, MD, UCLA School of Medicine

                                     Louis M. Weiner

 

“Kidney-Specific Tumor Vaccine Directed Against Kidney Tumor Antigen G-250”

US Patent No. 09/873,708

Filed February 13, 2000

UCLA Ref No: LA99-270-1

Inventors:                   Arie Belldegrun, MD, UCLA School of Medicine

                                     Cho-Lea Tso, MA, UCLA School of Medicine

 

Publications: (Most recent)

 

 

Lam JS, Shvarts O, Belldegrun A. Kidney Cancer Management 2004: An Update for the Practicing General Urologist. Curr Urol Rep 5:1-3, 2004.

 

Shvarts O, Lam JS, Figlin RA, Belldegrun A. Heat Shock-Peptide Complex Vaccine as Adjuvant Therapy for High Risk Patients with Resected Renal Cell Carcinoma. Curr Urol Rep 5:11:12, 2004.

 

Kim HL, Lam JS, Belldegrun A: The Role of Lymphadenectomy in Renal Cell Carcinoma. Curr Urol Rep 5(1): 25-29, 2004. Review.

 

Kim HL, Zisman A, Han K, Figlin RA, Belldegrun A.  Prognostic Significance of Venous Thrombus in Renal Cell Carcinoa:  Is Renal Vein and Inferior Vena Cava Involvement Different?  J Urol 171:588-591, 2004.

 

Palapattu GS, Kim HL, Belldegrun A.  Advances in the Treatment of Genitourinary Cancer: Highlights from the 3rd Annual Society of Urologic Oncology Meeting. Rev Urol 5:232:234, 2004.

 

Foon K, Yang X, Weiner L, Belldegrun A, Figlin R, Crawford J, Rowinsky E, Dutcher J, Vogelzang N, Gollub J, Thompson J, Schwartz G, Bukowski R, Roskos L, Schwab G: Preclinical and Clinical Evaluation of ABX-EGF: A Fully Human Anti-Epidermal Growth Factor Receptor Antibody. Int'l J Radiation Oncology Biol. Phys.Vol. 58, No. 3: 984-990, 2004.