John Lam, MD Fellowship in Endourology Location: 63-276   Phone: 310-825-1094 Email: jlam@mednet.ucla.edu

Educational Background

Professional Memberships

Academic & Medical Staff Appointments

Awards & Honors

Additional Information

RESEARCH EXPERIENCE AND PROFESSIONAL TRAINING:

2003-2005 David Geffen School of Medicine at UCLA, Department of Urology, Urologic Oncology Laboratory, Los Angeles, California.
 Position: urologic oncology research fellow
 Principal Investigator: Arie S. Belldegrun, MD.
Research involving the evaluation of genetically engineered dendritic cells expressing carbonic anhydrase IX (CA IX) or CA IX-granulocyte/macrophage-colony stimulating factor (GM-CSF) fusion protein to generate protective and active immunity for the prevention and treatment of tumors expressing CA IX and defining the immunological mechanisms governing CA IX-DC generated immunity.  Research also involving the development of second-generation tissue microarrays to provide prognostic information on patients with advanced kidney cancer and identifying those patients most likely to benefit from CA IX-directed therapy.  Research also involving the use of hypoxia-inducible factor-1a (HIF-1a) as a potential target for immunotherapy of renal cell carcinoma.

1994-1996 National Cancer Institute, Surgery Branch, Immunotherapy Section, Bethesda, Maryland.
 Position: HHMI-NIH Research Scholar
 Preceptor: Patrick Hwu, MD.
 Chief: Steven A. Rosenberg, MD, PhD.
Research involved gene modification of antitumor T cells for immunotherapy of cancer patients.  Research efforts demonstrated receptor expression level is an important factor in retroviral-target interactions and gene transfer efficiency in human lymphocytes was improved 4- to 18-fold over previous gene transfer protocols using the gibbon ape leukemia retrovirus.  A novel quantitative polymerase chain reaction (PCR) assay was developed to determine transduction efficiency.  In addition, studies involved use of tumor antigens in the development of potential therapeutic vaccines.  Research efforts demonstrated dendritic cells pulsed with tumor antigens or recombinant poxviruses encoding tumor antigens were effective in prolonging survival and treating established pulmonary metastases in a murine tumor model.

 
1993-1994 Wayne State University School of Medicine, Department of Urology, Tumor Immunology Laboratory, Detroit, Michigan.
 Position: student research assistant
 Principal Investigators: Gilda G. Hillman, PhD and Gabriel P. Haas, MD.
Research efforts demonstrated that local irradiation can greatly enhance effectiveness of systemic immunotherapy in a variety of murine tumor models.

1993 National Institute of Allergy and Infectious Diseases, Laboratory of Immunology, Molecular Biology Section, Bethesda, Maryland.
 Position:  NIH summer research fellow
 Principal Investigator: David H. Margulies, MD, PhD.
Research focused on development of a bacterial expression system for a genetically engineered soluble, single-chain class I major histocompatibility complex molecule.

1990-1992 University of Michigan Medical School, Department of Surgery, Oncology Research Laboratory, Ann Arbor, Michigan.
 Position:  student research assistant
 Principal Investigator: Bernard A. Fox, PhD.
Research focused on studying cytokine expression levels in murine T cell clones transduced with various human cytokine genes.

1989-1991 University of Michigan Medical School, Department of Surgery, Transplantation Research Laboratory, Ann Arbor, Michigan.
 Position:  student research fellow/undergraduate honors thesis candidate
 Principal Investigator: Robert M. Merion, MD.
Research efforts demonstrated that portal venous inoculation (PVI) of donor strain mononuclear cells into recipient animals significantly inhibited mixed lymphocyte culture reactivity (MLC) and liposome-mediated reticuloendothelial system (RES) blockage returns proliferation of lymphocytes back to control levels of MLC reactivity.  These results suggested that an intact RES is necessary at the time of PVI in order for inhibition of MLC to occur.
 

BIBLIOGRAPHY:

 COMPLETED MANUSCRIPTS (PEER REVIEWED)-

1.  Hillman, G.G.; Younes, E.; Visscher, D.; Ali, E.; Lam, J.S.; Montecillo, E.; Pontes, J.E.; Haas, G.P.; and Puri, R.K.  Systemic Treatment with Interleukin-4 Induces Regression of Pulmonary Metastases in a Murine Renal Cell Carcinoma Model.  Cellular Immunology 160:257-263 (1995).

2.  Lam, J.S.; Hillman; G.G.; Ali, E.; Maughan, R.L.; Montecillo, E.J.; Pontes, J.E.; and Haas, G.P.  Effect of Local Tumor Irradiation and Interleukin-2 Therapy in Separate Murine Tumor Models.  Journal of Immunotherapy 18:28-34 (1995).

3.  Lam, J.S.; Reeves, M.E.; Cowherd, R.; Rosenberg, S.A.; and Hwu, P.  Improved Gene Transfer into Lymphocytes Using Retroviruses with the Gibbon Ape Leukemia Virus Envelope.  Human Gene Therapy 7:1419-1426 (1996).

4.  Reeves, M.E.; Royal, R.E.; Lam, J.S.; Rosenberg, S.A.; and Hwu, P.  Retroviral Transduction of Human Dendritic Cells with a Tumor-Associated Antigen Gene.  Cancer Research 56:5672-5677 (1996).

5.  Hillman, G.G.; Younes, E.; Visscher, D.; Hamzavi, F.; Kim, S.; Lam, J.S.; Montecillo, E.J.; Ali, E.; Pontes, J.E.; Puri, R.K.; and Haas, G.P.  Inhibition of Murine Renal Carcinoma Pulmonary Metastases by Systemic Administration of Interferon Gamma: Mechanism of Action and Potential for Combination with Interleukin-4.  Clinical Cancer Research 3:1799-1806 (1997).

6.  Specht, J.M.; Wang, G.; Do, M.T.; Lam, J.S.; Royal, R.E.; Reeves, M.E.; Rosenberg, S.A.; and Hwu, P.  Dendritic Cells Retrovirally Transduced with a Model Antigen Gene Are Therapeutically Effective against Established Pulmonary Metastases.  Journal of Experimental Medicine 186:1213-1221 (1997).

7.  Cher, M.L.; Bianco, Jr., F.J.; Lam, J.S.; Davis, L.P.; Grignon, D.J.; Sakr, W.A.; Banerjee, M.; Pontes, J.E.; and Wood, Jr., D.P.  Limited Role of Radionuclide Bone Scintigraphy in Patients with Prostate Specific Antigen Elevations after Radical Prostatectomy.  Journal of Urology 160:1387-1391 (1998).

8.  Lam, J.S.; Greene, T.D.; and Gupta, M.  Treatment of Proximal Ureteral Calculi: Holmium:YAG Laser Ureterolithotripsy Versus Extracorporeal Shock Wave Lithotripsy.  Journal of Urology 167:1972-1976 (2002).

9.  Royal, R.E.; Kershaw, M.H.; Reeves, M.E.; Wang, G.; Daly, T.; Treisman, J.; Lam, J.; and Hwu, P. Increased Functional Expression of Transgene in Primary Human Lymphocytes Using Retroviral Vectors Modified with IRES and Splicing Motifs.  Gene Therapy 9:1085-1092 (2002).

10.  Kaplan, S.A.; Ghafar, M.A.; Volpe, M.A.; Lam, J.S.; Fromer, D.; and Te, A.E.  PSA Response to Finasteride Challenge in Men with a Serum Prostate-Specific Antigen Greater than 4 ng/mL and Previous Negative Prostate Biopsy: Preliminary Study.  Urology 60:464-468 (2002).

11.  Lam, J.S. and Gupta, M.  Tips and Tricks for the Management of Retained Ureteral Stents.  Journal of Endourology 16:733-741 (2002).

12.  Lam, J.S.; Romas, N.A.; and Lowe, F.C.  Long-Term Treatment with Finasteride in Men with Symptomatic Benign Prostatic Hyperplasia: 10-Year Follow-up.  Urology 61:354-358 (2003).

13.  Lam, J.S.; Benson, M.C.; O’Donnell, M.A.; Sawczuk, A.; Gavazzi, A.; Wechsler, M.H.; and Sawczuk, I.S.  Bacillus Calmete-Guérin plus Interferon-a2B Intravesical Therapy Maintains an Extended Treatment Plan for Superficial Bladder Cancer with Minimal Toxicity.  Urologic Oncology: Seminars and Original Investigations (2003).

14.  Lam, J.S.; Cooper, K.L.; Greene, T.D.; and Gupta, M.  Impact of Hydronephrosis and Renal Function on Treatment Outcomes: Antegrade versus Retrograde Endopyelotomy.  Urology 61:1107-1112 (2003).

15.  Lam, J.S.; Cheung, Y.K.; Benson, M.C.; and Goluboff, E.T.  Comparison of the Predictive Accuracy of Serum Prostate Specific Antigen Levels and Prostate Specific Antigen Density in the Detection of Prostate Cancer in Hispanic-American and White Men.  Journal of Urology 170:451-456 (2003).

16.  Lam, J.S.; Bingham, J.B.; and Gupta, M.:  Endoscopic Management of Fibroepithelial Polyps of the Renal Pelvis and Ureter.  Urology 62:810-813 (2003).

17.  Lam, J.S.; Desai, M.; Mansukhani, M.M.; Benson, M.C.; and Goluboff, E.T.:  Is Hispanic Race an Independent Risk Factor for Pathologic Stage in Patients Undergoing Radical Prostatectomy?  Journal of Urology 170:2288-2291 (2003).

18.  Okeke, Z.; Lam, J.S.; and Gupta, M.:  Use of a Ureteral Access Catheter to Facilitate Removal of Renal Calculi during Extracorporeal Shock Wave Lithotripsy.  Urology 63: (2004).

19.  Mukouyama, H.; Janzen, N.K.; Hernandez, J.M.; Lam, J.S.; Caliliw, R.; Wang, A.Y.; Figlin, R.A.; Belldegrun, A.S.; and Zeng, G.:  Generation of Kidney Cancer Specific Anti-Tumor Immune Responses Using Peripheral Blood Monocytes Transduced with a Recombinant Adenovirus Encoding Carbonic Anhydrase 9.  Clinical Cancer Research 10:1421-1429 (2004).

20.  Patard, J.J.; Shvarts, O.; Lam, J.S.; Pantuck, A.J.; Kim, H.L.; Ficarra, V.; Cindolo, L.; Han, K.R.; De La Taille, A.; Tostain, J.; Artibani, W.; Abbou, C.C.; Lobel, B.; Chopin, D.K.; Figlin, R.A.; Mulders, P.F.A.; and Belldegrun, A.S.:  Safety and Efficacy of Partial Nephrectomy for all T1 Tumors Based on an International Multicenter Experience.  Journal of Urology 171: (2004).

21.  Patard, J.J.; Kim, H.L.; Dorey F.J.; Lam, J.S.; Pantuck, A.J.;.Zisman, A.; Ficarra, V.; Han, K.R.; Cindolo, L.; De La Taille, A.; Tostain, J.; Artibani, W.; Dinney, C.P.; Wood, C.G.; Swanson, D.A.; Abbou, C.C.; Lobel, B.; Mulders, P.F.A.; Chopin, D.K.; Figlin, R.A.; and Belldegrun, A.S.:  The Use of UISS (UCLA Integrated Staging System) to Predict Survival in Renal Cell Carcinoma: An International Multicenter Study in 4202 Patients.  Journal of Clinical Oncology (2004).

22.  Lam, J.S.; Sclar, J.D.; Desai, M.; Mansukhani, M.M.; Benson, M.C.; and Goluboff, E.T.:  Is Hispanic Race an Outcome Predictor Following Radical Prostatectomy for Prostate Cancer?  (submitted, 2004).

23.  Lam, J.S.; Royal, R.E.; Reeves, M.E.; Wang, G; Restifo, N.P.; Rosenberg, S.A.; and Hwu, P.:  Dendritic Cells Pulsed with Model Tumor Antigens Can Effectively Treat Established Pulmonary Metastases.  (in preparation, 2004).

24.  Shvarts, O.; Lam, J.S.; Kim, H.L.; Han, K.R.; and Belldegrun, A.S.:  ECOG Performance Status Predicts Bone Metastasis in Patients Presenting with Renal Cell Carcinoma.  (submitted, 2004).

25.  Shvarts, O.; Said, J.W.; Lam, J.S.; Pantuck, A.J.; Seligson, D.; Aldridge, M.E.; Bui, M.H.; Liu, X.; Horvath, S.; and Belldegrun, A.S.:  Clinical, Pathological, and Molecular Correlations of Necrosis in the Primary Tumor of Patients with Renal Cell Carcinoma.  (submitted, 2004).

26.  Shvarts, O.; Seligson, D.; Lam, J.S.; Shi, T.; Horvath, S.; Figlin, R.A.; Belldegrun, A.S.; and Pantuck, A.J.:  P53 is an Independent Predictor of Tumor Recurrence and Progression after Nephrectomy for Patients with Localized Renal Cell Carcinoma: Implications for Surveillance and Adjuvant Clinical Trials.  (submitted, 2004).

27.  Lam, J.S.; Kim, H.L.; Shvarts, O.; Pantuck, A.J.; and Belldegrun, A.S.:  Lymphadenectomy Practice Patterns at Radical Nephrectomy Amongst Urology Centers of Excellence.  (in preparation, 2004).

28.  Lam, J.S.; Shvarts, O.; Alemozaffar, M.; Kim, H.L.; Li, N.; Li, G.; Pantuck, A.J.; Smith, R.B.; and Belldegrun, A.S.:  Nephron-Sparing Surgery as the New Gold Standard for T1 (=7 cm) Renal Cell Carcinoma: Results of a Contemporary UCLA Series.  (in preparation, 2004).

29.  Lam, J.S.; Shvarts, O.; Rao, P.N.; Liu, X.; Li, G.; Langhorn, C.; Figlin, R.A.; Belldegrun, A.S.; and Pantuck, A.J.:  Prognostic Impact of Chromosomal Alterations in Renal Cell Carcinoma Following Surgical Resection.  (in preparation, 2004).

30.  Lam, J.S.; Shvarts, O.; Figlin, R.A.; and Belldegrun, A.S.:  Prognostic Factors and Long-Term Outcome Following Resection of Renal Cell Carcinoma with Right Atrial Extension: The UCLA Experience.  (in preparation, 2004).

31.  Lam, J.S.; Shvarts, O.; Belldegrun, A.S.; and Pantuck, A.J.:  Impact of Adrenalectomy on Recurrence and Survival for Patients Undergoing Surgical Resection for Renal Cell Carcinoma.  (in preparation, 2004).

32.  Lam, J.S.; Yamashiro, J.; Said, J.W.; and Reiter, R.E.:  Prostate Stem Cell Antigen Expression in Metastatic Prostate Cancer.  (in preparation, 2004).

33.  Okeke, Z.; Lam, J.S.; Kozakowski, K.A.; and Gupta, M.:  Impact of Obesity on Ureteroscopic Management of Upper Urinary Tract Calculi.  (in preparation, 2004).

34.  Okeke, Z., Lam, J.S.; Shah, J.; and Gupta, M.:  Comparison of Percutaneous Nephrolithotomy in Patients with Recurrent Nephrolithiasis: Primary versus Previous Open Stone Surgery.  (in preparation, 2004).

 CASE REPORTS-

1.  Lam, J.S.; Hensle, T.W.; Debelenko, L.; Granowetter, L.; and Tennenbaum, S.Y.:  Organ-Confined Primitive Neuroectodermal Tumor Arising from the Kidney.  Journal of Pediatric Surgery 38:619-621 (2003).

2.  Lam, J.S.; Borczuk, A.C.; and Franklin, J.R.:  Metastatic Leydig Cell Tumor of the Testicle in a Young African American Male.  Canadian Journal of Urology 10:2074-2076 (2003).

 REVIEWS, CHAPTERS, AND EDITORIALS-

1.  Lam, J.S.; Volpe, M.A.; and Kaplan, S.A.:  Use of Prostatic Stents for the Treatment of Benign Prostatic Hyperplasia in High-Risk Patients.  Current Urology Reports 2:277-284 (2001).

2.  Goluboff, E.T.; Lam, J.S.; Katz, A.E.; and Olsson, C.:  Radical Prostatectomy for the Treatment of Prostate Cancer.  In Movsas, B.; Hudes, G; and Olsson, C. (eds): Atlas of Genitourinary Oncology.  Philadelphia, W.B. Saunders, Chapter 2, pp. 17-44 (2002).

3.  Lam, J.S.; Volpe, M.A.; and Kaplan, S.A.:  Transurethral Resection and Incision of the Prostate.  Atlas of the Urologic Clinics of North America 10:27-43 (2002).

4.  Lam, J.S. and Gupta, M.:  Laparoscopic Ablation of Renal Cysts.  In Hemal A.K. (ed): Contemporary Trends in Laparoscopic Urologic Surgery.  New Delhi, B.I. Churchill Livingston PVT LTD, Chapter 11, pp. 81-94 (2002).

5.  Lam, J.S. and Gupta, M.:  Ureteral Stents.  In Stoller, M.L. and Meng, M.V. (eds): Urinary Stone Disease: The Practical Guide to Medical and Surgical Mangement.  Totowa, Humana Press, Chapter 25, pp. (2004).

6.  Lam, J.S. and Gupta, M.:  Ureteroscopic Management of Upper Tract Transitional Cell Carcinoma.  Urologic Clinics of North America 31:115-128 (2004).

7.  Lam, J.S. and Gupta, M.:  Ureteroenteric Anastomotic Strictures.  In Smith, A.D.; Badlani, G.H.; Bagley, D.H.; Clayman, R.V.; Jordan, G.H.; Kavoussi, L.R.; Lee, B.R.; Lingeman, J.E.; Preminger, G.M.; and Segura, J.W. (eds): Smith’s Textbook of Endourology, ed 2.  St. Louis, Quality Medical Publishing, Chapter 104, pp. (2004).

8.  Lam, J.S.; Cooper, K.L.; and Kaplan, S.A.:  Changing Aspects in the Evaluation and Treatment of Patients with Benign Prostatic Hyperplasia.  Medical Clinics of North America 88:281-308 (2004).

9.  Lam, J.S. and Gupta, M.:  Update on Ureteral Stents.  Urology (2004).

10.  Shvarts, O; Lam, J.S.; Kim, H.; and Belldegrun, A.:  Staging of RCC: Current Concepts.  British Journal of Urology International (2004).

11.  Shvarts, O; Lam, J.; Figlin, R.; and Belldegrun, A.:  Heat Shock Protein Complex Vaccine as Adjuvant Therapy for High-Risk Patients with Resected Renal Cell Carcinoma.  Current Urology Reports 5:11-12 (2004).

12.  Lam, J.S.; Shvarts, O.; and Belldegrun, A.S.:  Kidney Cancer Management 2004: An Update for the Practicing General Urologist.  Current Urology Reports 5:1-3 (2004).

13.  Kim, H.L.; Lam, J.S.; and Belldegrun, A.S.:  The Role of Lymphadenectomy in Renal Cell Carcinoma.  Current Urology Reports 5:25-29 (2004).

14.  Shvarts, O.; Han, K.R.; Lam, J.S.; and Belldegrun, A.S.:  Primary Leiomyosarcoma in the Inferior Vena Cava Presenting as a Renal Mass.  Reviews in Urology (2004).

15.  Lam, J.S.; Shvarts, O.; Figlin, R.A.; and Belldegrun, A.S.:  Renal Cell Carcinoma 2004: New Frontiers in Staging, Prognostification, and Targeted Molecular Therapy.  Journal of Urology (2004).

16.  Lam, J.S.; Shvarts, O.; and Pantuck, A.J.:  Changing Concepts in the Surgical Management of Renal Cell Carcinoma.  European Urology (2004).

17.  Lam, J.S.; Shvarts, O.; and Belldegrun, A.S.:  Prostate Cryotherapy – Why and What’s the Evidence?.  European Urology Today (2004).

18.  Shvarts, O.; Lam, J.S.; and Belldegrun, A.S.:  Meeting Review: 4th Annual Meeting of the Society of Urologic Oncology 2003.  Reviews in Urology (2004).

19.  Shvarts, O.; Lam, J.; and Belldegrun, A.:  Prognostic Factors in Renal Cell Carcinoma.  Biotherapy: Considerations for Oncology Nurses (2004).

20. Lam, J.S.; Belldegrun, A.S.; and Figlin, R.A.:  Renal Cell Carcinoma: Tissue Array Based Predictors of Pathobiology, Prognosis, Response to Treatment, and Identification of Potential Molecular Targets for Therapy.  Clinical Cancer Research (2004).

21.  Shvarts, O.; Lam, J.; Belldegrun, A; Pantuck, A.:  Follow-Up Guidelines for Patients with Renal Cell Carcinoma After Nephrectomy.  Contemporary Urology (2004).

22.  Kim, H.L.; Lam, J.S.; and Belldegrun, A.S.:  Surgical Management of Renal Cell Carcinoma: Role of Lymphadenectomy in Renal Cell Carinoma Surgery.  In Vogelzang, N.J.; Shipley, W.U.; Scardino, P.T.; Coffey, D.S.; and Miles B.J. (eds): Comprehensive Textbook of Genitourinary Oncology.  Philadelphia, Lippincott Williams and Wilkens, Chapter, pp. (2004).

23.  Lam, J.S.; Shvarts, O.; Belldegrun, A.S.:  Cryotherapy of Prostate Cancer.  Contemporary Urology (2004).

24.  Lam, J.S.; Shvarts, O.; Belldegrun, A.S.:  Salvage Cryosurgery of the Prostate after Radiation Failure.  Reviews in Urology (Supplement) (2004).

25.  Lam, J.S.; Shvarts, O.; Belldegrun, A.S.:  Cryosurgery of Renal Tumors.  Kidney Cancer Journal (2004).

ABSTRACTS, PRELIMINARY COMMUNICATIONS, PANEL DISCUSSIONS-

1.  Lam, J.S. and Merion, R.M.: Kinetics of Tolerance Induction Following Portal Venous Mononuclear Cell Inoculation.  37th Annual University of Michigan Student Biomedical Research Forum, 1991.

2.  Lam, J.S. and Fox, B.A.: CD3-Mediated Regulation of Tumor Necrosis Factor Secretion by a Murine T-Cell Clone Transduced with the Gene for Human Tumor Necrosis Factor a.  2nd Annual Southwestern Michigan Immunology Poster Session, Abstract 4, 1991; 37th Annual University of Michigan Student Biomedical Research Forum, 1991.

3.  Lam, J.S.; Culver, K.W.; Shu, S.; Blaese, R.M.; and Fox, B.A.: Transduction of Human IL-1b Gene into a T Cell Clone is Associated with an Alteration in TNF Secretion.  76th Annual Meeting of the Federation of American Societies for Experimental Biology, FASEB Journal 6:1998A, Abstract 6147, 1992; Moses Gunn Annual Research Conference, 1992.

4.  Fox, B.A.; Lam, J.; Culver, K.W.; and Blaese, R.M.: CD3 Regulation of Human IL-1b Secretion in Murine T Cells: Model for Regulated Delivery of Novel Gene Products.  83rd Annual Meeting of the American Association for Cancer Research, Proceedings of the American Association for Cancer Research 33:494, Abstract 2954, 1992; Moses Gunn Annual Research Conference, 1992.

5.  Lam, J.S.; Culver, K.W.; Shu, S.; Blaese, R.M.; and Fox, B.A.: Transduction of Human IL-1b Gene into a Murine T Cell Clone is Associated with CD3/TCR Regulated Secretion of TNF.  8th International Congress of Immunology, 1992; Wayne State University Medical Student Research Symposium, 1992.

6.  Lam, J.S.; Kozlowski, S.; Mage, M.G.; and Margulies, D.H.: Expression of a Soluble, Single-Chain Class I Major Histocompatibility Complex Molecule in Bacteria.  Wayne State University Medical Student Research Symposium, 1993; 3rd Annual National Institutes of Health Summer Research Program Poster Day, Abstract 86, 1993.

7.  Hillman, G.G.; Lam, J.S.; Younes, E.; Ali, E.; Montecillo, E.; Pontes, J.E.; and Haas, G.P.: Local Tumor Irradiation Enhances the Therapeutic Effect of IL-2 Therapy in Various Murine Tumor Models.  86th Annual Meeting of the American Association for Cancer Research, Proceedings of the American Association for Cancer Research 36:496, Abstract 2954, 1995.

8.  Lam, J.S.; Cowherd, R.; Rosenberg, S.A.; and Hwu, P.: Expression of GLVR-1 and GLVR-2 on Human Lymphocytes: Relationship to Retroviral Mediated Gene Transduction.  87th Annual Meeting of the American Association for Cancer Research, Proceedings of the American Association for Cancer Research 37:343, Abstract 2343, 1996.

9.  Lam, J.S.; Royal, R.E.; Reeves, M.E.; Wang, G.; Restifo, N.P.; Rosenberg, S.A.; and Hwu, P.: Dendritic Cells Pulsed with Model Tumor Antigens Effectively Treat Established Pulmonary Metastases.  Keystone Symposia: Cellular Immunology and the Immunotherapy of Cancer-III, Abstract 118, 1997.

10.  Specht, J.M., Do, M., Lam, J., Wang, G., Reeves, M., Royal, R., Rosenberg, S.A., and Hwu, P.: Dendritic Cells Retrovirally Transduced with a Model Tumor Antigen Gene are Therapeutically Effective Against Established Pulmonary Metastases.  88th Annual Meeting of the American Association of Cancer Research, Proceedings of the American Association for Cancer Research 38:616-617, Abstract 4140, 1997.

11.  Bianco, Jr., F.J.; Lam, J.S.; Davis, L.P.; Grignon, D.J.; Sakr, W.A.; Pontes, J.E.; Wood, Jr., D.P.; and Cher, M.L.: Limited Role of Radionuclide Bone Scan in Patients with Prostate Cancer Recurrence after Radical Prostatectomy.  93rd Annual Meeting of the American Urological Association, Journal of Urology 159 (Supplement):288, Abstract 1111, 1998.

12.  Lam, J.S.: Outcomes of Men Treated with Long-Term Finasteride for Symptomatic Benign Prostatic Hyperplasia: 10 Year Follow-up.  Ferdinand C. Valentine Urology Prize Essay Meeting, Abstract 99, 2000.

13.  Lam, J.S.; Benson, M.C.; Sawczuk, A.; Gavazzi, A.; Wechsler, M.; and Sawczuk, I.S.: Low Dose BCG Plus IFNa-2B Intravesical Therapy for Superficial Bladder Cancer Allows for Symptom Tolerance and Maintenance of Extended Treatment Plan.  37th Annual Meeting of the American Society of Clinical Oncology, Program/Proceedings of the American Society of Clinical Oncology 20:176b, Abstract 2454, 2001.

14.  Lam, J.S.; Greene, T.D.; and Gupta, M.: Treatment of Proximal Ureteral Calculi: Holmium: YAG Laser Ureterolithotripsy Versus Extracorporeal Shock Wave Lithotripsy.  19th World Congress on Endourology and SWL, Journal of Endourology 15 (Supplement 1):80, Abstract C3/P10, 2001.

15.  Lam, J.S.; Benson, M.C.; O’Donnell, M.A.; Sawczuk, A.; Gavazzi, A.; Wechsler, M.; and Sawczuk, I.S.: Bacillus Calmete-Guérin Plus Interferon Alfa 2B Intravesical Therapy Maintains an Extended Treatment Plan for Superficial Bladder Cancer with Minimal Toxicity.  97th Annual Meeting of the American Urological Association, Journal of Urology 167 (Supplement):190, Abstract 765, 2002.

16.  Lam, J.S.; McKiernan, J.M.; Anastasiadis, A.G.; Benson, M.C.; and Goluboff, E.T.: Comparison of the Predictive Accuracy of Serum PSA Levels and PSA Density in the Detection of Prostate Cancer in Caucasian and Hispanic-American Men.  97th Annual Meeting of the American Urological Association, Journal of Urology 167 (Supplement):207, Abstract 833, 2002.

17.  Ghafar, M.; Lam, J.; Littlejohn, J.O.; and Kaplan, S.A.: Use of Finasteride as a Diagnostic Tool in Evaluating Men with a Serum PSA > 4 and Previous Negative Prostate Biopsy.  97th Annual Meeting of the American Urological Association, Journal of Urology 167 (Supplement):267, Abstract 1051, 2002.

18.  Lam, J.S.; Romas, N.A.; and Lowe, F.C.: Long-term Treatment with Finasteride in Men with Symptomatic Benign Prostatic Hyperplasia: 10-Year Follow-up.  97th Annual Meeting of the American Urological Association, Journal of Urology 167 (Supplement):376, Abstract 1495, 2002.

19.  Lam, J.S.: Use of Finasteride as a Diagnostic Tool in Evaluating Men with Persistently Elevated Serum Prostate-Specific Antigen Levels Following Previously Negative Prostate Biopsies.  Ferdinand C. Valentine Urology Prize Essay Meeting, Abstract 81, 2002.

20.  Lam, J.S.; Desai, M.; Benson, M.C.; and Goluboff, E.T.: Is Hispanic Race an Independent Risk Factor for Pathologic Stage in Patients Undergoing Radical Retropubic Prostatectomy? 98th Annual Meeting of the American Urological Association, Journal of Urology 169 (Supplement):300-301, Abstract 1167, 2003.

21.  Lam, J.S.; Cooper, K.L.; Greene, T.D.; and Gupta, M.  Impact of Hydronephrosis and Renal Function on Treatment Outcomes: Antegrade versus Retrograde Endopyelotomy.  21st World Congress on Endourology and SWL, Journal of Endourology 17 (Supplement 1):80, Abstract C3/P27, 2003.

22.  Lam, J.S.; Bingham, J.B.; and Gupta, M.: Endoscopic Management of Fibroepithelial Polyps of the Renal Pelvis and Ureter.  21st World Congress on Endourology and SWL, Journal of Endourology 17 (Supplement 1):80, Abstract C3/P30, 2003.

23.  Lam, J.S.; Han, K.R.; Janzen, N.K.; Shvarts, O.; McWhorter, V.C.; Kim, H.L.; Pantuck, A.J.; Zisman, A.; Figlin, R.A.; Dorey, F.J.; Said, J.W.; and Belldegrun, A.S.: Cystic Renal Cell Carcinoma: Biology and Clinical Behavior.  4th Annual Meeting of the Society of Urologic Oncology, Abstract 73, 2003.

24.  Lam, J.S.; Han, K.R.; Shvarts, O.; Bleumer, I.; Pantuck, A.J.; Kim, H.L.; Dorey, F.J.; Janzen, N.K.; Zisman, A.; Dinney, C.P.; Wood, C.G.; Swanson, D.A.; Said, J.W.; Figlin, R.A.; Mulders, P.F.A.; and Belldegrun, A.S.: Validation of an Integrated Staging System Towards Improved Prognostication of Patients with Localized Renal Cell Carcinoma in an International Population.  4th Annual Meeting of the Society of Urologic Oncology, Abstract 74, 2003.

25.  Mukouyama, H.; Janzen, N.K.; Hernandez, J.M.; Shvarts, O.; Lam, J.S.; Caliliw, R.; Wang, A.Y.; Aldridge, M.E.; Figlin, R.A.; Belldegrun, A.S.; and Zeng, G.: Generation of Kidney Cancer Specific Anti-Tumor Immune Responses Using Peripheral Blood Monocytes Transduced with a Recombinant Adenovirus Encoding Carbonic Anhydrase 9.  4th Annual Meeting of the Society of Urologic Oncology, Abstract 77, 2003.

26.  Shvarts, O.; Lam, J.S.; Kim, H.L.; Han, K.R.; and Belldegrun, A.S.: ECOG Performance Status Predicts Bone Metastasis in Patients Presenting with Renal Cell Carcinoma.  4th Annual Meeting of the Society of Urologic Oncology, Abstract 81, 2003.

27.  Lam, J.S.; Shvarts, O.; Alemozaffar, M.; Kim, H.L.; Wang, H.J.; Pantuck, A.J.; Smith, R.B.; and Belldegrun, A.S.: Nephron-Sparing Surgery as the New Gold Standard for T1 (=7 cm) Renal Cell Carcinoma: Results of a Contemporary UCLA Series.  99th Annual Meeting of the American Urological Association, Journal of Urology 171 (Supplement):, Abstract, 2004.

28.  Lam, J.S.; Shvarts, O.; Rao, P.N.; Liu, X.; Li, G.; Langhorn, C.; Figlin, R.A.; Belldegrun, A.S.; and Pantuck, A.J.: Prognostic Impact of Chromosomal Alterations in Renal Cell Carcinoma Following Surgical Resection.  99th Annual Meeting of the American Urological Association, Journal of Urology 171 (Supplement):, Abstract , 2004.

29.  Zeng, G.; Lam, J.S.; Figlin, R.A.; and Belldegrun, A.S.: Identification of T Cell Clones that Recognize Shared Renal Cell Carcinoma Antigens.  99th Annual Meeting of the American Urological Association, Journal of Urology 171 (Supplement):, Abstract, 2004.

30.  Mukouyama, H.; Yao, M.; Seligson, D.; Lam, J.S.; Nagashima, Y.; Inayama, Y.; Shvarts, O.; Figlin, R.A.; Zeng, G.; and Belldegrun, A.S.: Carbonic Anhydrase IX (CA IX) Expression and VHL Gene Alteration as Predictors of Survival in Renal Cell Carcinoma.  99th Annual Meeting of the American Urological Association, Journal of Urology 171 (Supplement):, Abstract, 2004.

31.  Shvarts, O.; Janzen, N.; Mukouyama, H.; Lam, J.S.; Caliliw, R.; Wang, A.Y.; Aldridge, M.E.; Belldegrun, A.; and Zeng, G.: RENCA/CAIX: A Murine Model of Renal Cell Carcinoma Expressing Carbonic Anhydrase IX.  99th Annual Meeting of the American Urological Association, Journal of Urology 171 (Supplement):, Abstract, 2004.

32.  Zeng, G.; Lam, J.S.; Caliliw, R.; Figlin, R.A.; Wang, Q.J.; and Belldegrun, A.S.: Identification of T Cell Clones that Recognize Shared Renal Cell Carcinoma Antigens.  95th Annual Meeting of the American Association of Cancer Research, Proceedings of the American Association for Cancer Research 45:1262, Abstract 5467, 2004.